Histopathological findings and canine pancreatic lipase immunoreactivity in normal dogs and dogs with inflammatory and neoplastic diseases of the pancreas.

ABSTRACT:

Background

Diagnosis of pancreatic diseases in dogs is still challenging because of variable clinical signs, which do not always correspond with clinical pathology and histopathological findings.

Objectives

To characterize inflammatory and neoplastic pancreatic diseases of dogs and to correlate these findings with clinical findings and canine pancreatic lipase immunoreactivity (cPLI) results.

Animals

Tissue specimens and corresponding blood samples from 72 dogs submitted for routine diagnostic testing.

Methods

Four groups were defined histologically: (1) normal pancreas (n = 40), (2) mild pancreatitis (n = 8), (3) moderate or severe pancreatitis (acute, n = 11; chronic, n = 1), and (4) pancreatic neoplasms (n = 12). An in-house cPLI ELISA (<180 μg/L, normal; >3

SUBMITTER: Aupperle-Lellbach H 

PROVIDER: S-EPMC7255677 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature