A multicenter randomized controlled trial of medium-chain triglyceride dietary supplementation on epilepsy in dogs.

ABSTRACT:

Background

Medium-chain triglyceride (MCT) enriched diet has a positive effect on seizure control and behavior in some dogs with idiopathic epilepsy (IE).

Objective

To evaluate the short-term efficacy of MCTs administered as an add-on dietary supplement (DS) to a variable base diet to assess seizure control and antiseizure drug's (ASD) adverse effect profiles.

Animals

Twenty-eight dogs with International Veterinary Epilepsy Task Force Tier II (IVETF) level diagnosis of treated IE with 3 or more seizures in the last 3 months were used.

Methods

A 6-month multicenter, prospective, randomized, double-blinded, placebo-controlled crossover trial was completed, comparing an MCT-DS with a control-DS. A 9% metabolic energy-based amount of MCT or control oil was suppleme

SUBMITTER: Berk BA 

PROVIDER: S-EPMC7255680 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature