Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study.

ABSTRACT:

Aims/hypothesis

Coronavirus disease-2019 (COVID-19) is a life-threatening infection caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus. Diabetes has rapidly emerged as a major comorbidity for COVID-19 severity. However, the phenotypic characteristics of diabetes in COVID-19 patients are unknown.

Methods

We conducted a nationwide multicentre observational study in people with diabetes hospitalised for COVID-19 in 53 French centres in the period 10-31 March 2020. The primary outcome combined tracheal intubation for mechanical ventilation and/or death within 7 days of admission. Age- and sex-adjusted multivariable logistic regressions were performed to assess the prognostic value of clinical and biological features with the endpoint. ORs are report

SUBMITTER: Cariou B 

PROVIDER: S-EPMC7256180 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature