First successful field evaluation of new, one-minute haemozoin-based malaria diagnostic device.

ABSTRACT:

Background

Early and accurate diagnosis of malaria is critical to the success of malaria elimination. However, the current mainstay of malaria diagnosis in the field, such as light microscopy and rapid diagnostic tests (RDTs), have limitations due to low parasite density or mutation in diagnostic markers.

Methods

We evaluated an inexpensive, robust, rapid, malaria diagnostic device, called Gazelle, that employs magneto-optical detection to identify haemozoin crystals (Hz) produced by all species of human malaria parasites in infected individuals. A beam of polarised light is passed through the lysed diluted blood sample under the influence of high (~.55T) and low magnetic fields. The difference in light transmission through the sample between the high and low magnetic fields

SUBMITTER: Kumar R 

PROVIDER: S-EPMC7256309 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature