Sex Differences in Case Fatality Rate of COVID-19: Insights From a Multinational Registry.

ABSTRACT:

Objectives

To confirm whether a relationship exists between male sex and coronavirus disease 2019 (COVID-19) mortality and whether this relationship is age dependent.

Patients and methods

We queried the COVID-19 Research Network, a multinational database using the TriNetX network, to identify patients with confirmed COVID-19 infection. The main end point of the study was all-cause mortality.

Results

A total of 14,712 patients were included, of whom 6387 (43%) were men. Men were older (mean age, 55.0±17.7 years vs 51.1±17.9 years; P<.001) and had a higher prevalence of hypertension, diabetes, coronary disease, obstructive pulmonary disease, nicotine dependence, and heart failure but a lower prevalence of obesity. Before propensity score matching (PSM), all-cause mortal

SUBMITTER: Alkhouli M 

PROVIDER: S-EPMC7256502 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature