Assessment of Language and Indexing Biases Among Chinese-Sponsored Randomized Clinical Trials.

ABSTRACT: Importance:Language and indexing biases may exist among Chinese-sponsored randomized clinical trials (CS-RCTs). Such biases may threaten the validity of systematic reviews. Objective:To evaluate the existence of language and indexing biases among CS-RCTs on drug interventions. Design, Setting, and Participants:In this retrospective cohort study, eligible CS-RCTs were retrieved from trial registries, and bibliographic databases were searched to determine their publication status. Eligible CS-RCTs were for drug interventions conducted from January 1, 2008, to December 31, 2014. The search and analysis were conducted from March 1 to August 31, 2019. Primary trial registries were recognized by the World Health Organization and the Drug Clinical Trial Registry Platform sponsored by the China Fo

SUBMITTER: Jia Y 

PROVIDER: S-EPMC7256669 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature