Health-related quality of life associates with change in FEV₁ in COPD: results from the COSYCONET cohort.

ABSTRACT:

Background

Forced expiratory volume in one second (FEV₁) characterizes the pathophysiology of COPD and different trajectories of FEV₁ decline have been observed in patients with COPD (e.g. gradual or episodic). There is limited information about the development of patient-reported health-related quality of life (HRQL) over the full range of the natural history of COPD. We examined the longitudinal association between change in FEV₁ and change in disease-specific and generic HRQL.

Methods

We analysed data of 1734 patients with COPD participating in the COSYCONET cohort with up to 3 years of follow-up. Patients completed the Saint George's Respiratory Questionnaire (SGRQ) and the EQ-5D Visual Analog Scale (EQ VAS). Change score models were used

SUBMITTER: Lutter JI 

PROVIDER: S-EPMC7257512 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature