Natural Reading in Parkinson's Disease With and Without Mild Cognitive Impairment.

ABSTRACT: Background: Patients with Parkinson's disease (PD) show eye movement abnormalities and frequently complain about difficulties in reading. So far, it is unclear whether basal ganglia dysfunction or cognitive impairment has a greater impact on eye movements during reading. Objective: To analyze eye movement behavior during a natural reading task with respect to cognitive state and dopaminergic therapy in PD and healthy controls. Methods: Eye movements of 59 PD patients and 29 age- and education-matched healthy controls were recorded during mute, self-paced reading of a text. 25 cognitively normal PD patients performed the task additionally in off medication state. Clinical assessment included a comprehensive neuropsychological test battery and the motor section of MDS-Un

SUBMITTER: Stock L 

PROVIDER: S-EPMC7258085 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature