CD36 Polymorphism (rs1761667) Was Associated with Fatty Liver in a Japanese Population

ABSTRACT: Abstract

Objectives

Nonalcohol fatty liver disease (NAFLD) is one of the considerable health problems in the world. NAFLD is a representative phenotype in the liver reflecting individual's lifestyle. Previous studies suggested that a single nucleotide polymorphism (SNP) in the CD36 gene was associated with dietary fat intake and fat metabolism. Therefore, we hypothesized that this SNP may be associated with fatty liver (FL) and NAFLD. We conducted this cross-sectional study to examine the association between two CD36 polymorphisms (rs1761667 and rs1527483) and FL and NAFLD in a Japanese population.

Methods

A total of 525 local residents participated in the health check-up in Yakumo town, Hokkaido, Japan. This cross-sectional study was conducted based on clinical informati

SUBMITTER: Fujii R 

PROVIDER: S-EPMC7258736 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature