Full-genome sequences of the first two SARS-CoV-2 viruses from India.

ABSTRACT:

Background & objectives

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has globally affected 195 countries. In India, suspected cases were screened for SARS-CoV-2 as per the advisory of the Ministry of Health and Family Welfare. The objective of this study was to characterize SARS-CoV-2 sequences from three identified positive cases as on February 29, 2020.

Methods

Throat swab/nasal swab specimens for a total of 881 suspected cases were screened by E gene and confirmed by RdRp (1), RdRp (2) and N gene real-time reverse transcription-polymerase chain reactions and next-generation sequencing. Phylogenetic analysis, molecular characterization and prediction of B- and T-cell epitopes for Indian SARS-CoV-2 sequences were undertaken.

Results</

SUBMITTER: Yadav PD 

PROVIDER: S-EPMC7258756 | biostudies-literature | 2020 Feb & Mar

REPOSITORIES: biostudies-literature