Comparison of the Acute Glycemic and Insulinemic Response of FossenceTM, a Short Chain Fructo-Oligosaccharide, Taken Alone, Added or Substituted into a Carbohydrate Load

ABSTRACT: Abstract

Objectives

To explore the physiological response to ingestion of FossenceTM, a short chain fructo-oligosaccharide, when taken alone or when added or substituted into a carbohydrate load.

Methods

In a randomized, controlled, cross-over design, 25 healthy subjects completed three phases (phase 1: 13M:12F; 41 ± 14y; 24.4 ± 2.2 kg/m²; phase 2: 13M:12F; 40 ± 14y; 24.5 ± 2.4 kg/m²; phase 3: 13M:12F; 41 ± 14y; 24.3 ± 2.6 kg/m²; Mean ± SD). On separate days, each subject received in Phase 1: 10 g FossenceTM(10FOS), 10 g Dextrose (10Dex) or a water control (Control); Phase 2: 50 g Dextrose alone (50Dex), Dextrose with 15 g FossenceTM(50Dex + 15FOS), 35 g Dextrose alone (35Dex) or Dextrose with 15 g FossenceTM(35Dex + 15FOS); and Phase 3 received: 50 g available carbohydra

SUBMITTER: Shah P 

PROVIDER: S-EPMC7258864 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature