Mineral Metabolism Disturbances and Arteriovenous Fistula Maturation.

ABSTRACT:

Background

The arteriovenous fistula (AVF) is central to haemodialysis treatment, but up to half of surgically created AVF fail to mature. Chronic kidney disease often leads to mineral metabolism disturbances that may interfere with AVF maturation through adverse vascular effects. This study tested associations between mineral metabolism markers and vein histology at AVF creation and unassisted and overall clinical AVF maturation.

Methods

Concentrations of fibroblast growth factor 23, parathyroid hormone, calcium, phosphate, and vitamin D metabolites: 1,25(OH)₂D, 24,25(OH)₂D, 25(OH)D, and bioavailable 25(OH)D were measured in pre-operative serum samples from 562 of 602 participants in the Haemodialysis Fistula Maturation Study, a multicentre, prospectiv

SUBMITTER: Kubiak RW 

PROVIDER: S-EPMC7259372 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature