From infancy to adulthood-Developmental changes in pulmonary quantitative computed tomography parameters.

ABSTRACT:

Purpose

Quantified computed tomography (qCT) is known for correlations with airflow obstruction and fibrotic changes of the lung. However, as qCT studies often focus on diseased and elderly subjects, current literature lacks physiological qCT values during body development. We evaluated chest CT examinations of a healthy cohort, reaching from infancy to adulthood, to determine physiological qCT values and changes during body development.

Method

Dose-optimized chest CT examinations performed over the last 3 years using a dual-source CT were retrospectively analysed. Exclusion criteria were age >30 years and any known or newly diagnosed lung pathology. Lung volume, mean lung density, full-width-at-half-maximum and low attenuated volume (LAV) were semi-automated quantified in 1

SUBMITTER: Gawlitza J 

PROVIDER: S-EPMC7259551 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature