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Are serum levels of inhibin A in second trimester predictors of adverse pregnancy outcome?


ABSTRACT: OBJECTIVE:During pregnancy, inhibin A is mainly derived from the placenta and regulates the implantation and differentiation of embryos. Our aim was to assess whether second trimester serum inhibin A was associated with an increased risk of adverse pregnancy outcomes. METHODS:We investigated the serum levels of Inhibin A during the second trimester in pregnancy, and analyzed associations between the Inhibin A and the risk of adverse pregnancy outcome. 12,124 pregnant women were enrolled in this study between January 2017 and July 2019 at the Obstetrics & Gynecology Hospital of Fudan University. Multivariate logistic regression analysis was conducted to estimate the relative risk between Inhibin A and adverse pregnancy outcome. RESULTS:Compared with the group without adverse pregnancy outco

SUBMITTER: Yue CY 

PROVIDER: S-EPMC7259778 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature