Ontology highlight
ABSTRACT:
SUBMITTER: Li W
PROVIDER: S-EPMC7259958 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
eLife 20200529
Errors can occur at any level during the replication and transcription of genetic information. Genetic mutations derived mainly from replication errors have been extensively studied. However, fundamental details of transcript errors, such as their rate, molecular spectrum, and functional effects, remain largely unknown. To globally identify transcript errors, we applied an adapted rolling-circle sequencing approach to <i>Escherichia coli</i>, <i>Bacillus subtilis</i>, <i>Agrobacterium tumefacien ...[more]