Individualizing Revascularization Strategy for Diabetic Patients With Multivessel Coronary Disease.

ABSTRACT:

Background

In patients with diabetes and multivessel coronary artery disease (CAD), the FREEDOM (Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease) trial demonstrated that, on average, coronary artery bypass grafting (CABG) was superior to percutaneous coronary intervention (PCI) for major acute cardiovascular events (MACE) and angina reduction. Nonetheless, multivessel PCI remains a common revascularization strategy in the real world.

Objectives

To translate the results of FREEDOM to individual patients in clinical practice, risk models of the heterogeneity of treatment benefit were built.

Methods

Using patient-level data from 1,900 FREEDOM patients, the authors developed models to predict 5-year MACE (a

SUBMITTER: Qintar M 

PROVIDER: S-EPMC7260040 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature