Neonatal oxygen saturations and blood pressure at school-age in children born extremely preterm: a cohort study.

ABSTRACT:

Objective

To explore the relationship between neonatal oxygen saturation and BP at age 6-7 years in a cohort of infants born extremely preterm.

Study design

Infants <28 weeks gestation were assigned to a higher or lower oxygen saturation target. Oximeter data were monitored throughout the neonatal period. A subset of survivors was seen at age 6. BP was measured and compared by group assignment, achieved saturations, and time spent in hypoxemia (saturations <80%).

Results

There was no difference in systolic or diastolic BP between assigned groups. Median achieved weekly oxygen saturation was not associated with BP. Longer duration of hypoxemia during the first week of age was associated with higher systolic BP.

Conclusions

Neither target nor actual median oxygen

SUBMITTER: Oren MS 

PROVIDER: S-EPMC7260090 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature