Diagnostic value of microRNA panel in endometrial cancer: A systematic review.

ABSTRACT:

Purpose

We conducted a systematic review to evaluate the overall diagnostic accuracy of miRNAs in detecting endometrial cancer.

Materials and methods

A systematic search of Medline, Embase, Cinahl and the Cochrane Controlled Register of Trials was performed to identify studies reporting on the diagnostic value of miRNA in EC patients. Included were diagnostic studies looking at miRNA expression in women diagnosed with endometrial cancer. Two reviewers independently selected studies and assessed quality of studies using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) score system. Data extraction was completed and the vote-counting strategy was used to rank miRNAs.

Results

26 studies were included with a total number of 1,400 EC patients reporting on

SUBMITTER: Donkers H 

PROVIDER: S-EPMC7260115 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature