Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent.

ABSTRACT: Coronavirus disease outbreak caused a severe public health burden all over the world. Salinomycin (SAL) is a broad-spectrum antibiotic that had drawn attention in selective targeting of cancer and viral infections. Recent drug screen identified SAL as a potent antiviral agent against SARS-CoV-2. In this hypothesis, we discuss the potential of pulmonary delivery of SAL using nanostructured lipid carriers (NLCs) against SARS-CoV-2.

SUBMITTER: Pindiprolu SKSS 

PROVIDER: S-EPMC7260485 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature