Thrombocytopenia and platelet course on hospital mortality in neurological intensive care unit: a retrospective observational study from large database.

ABSTRACT: BACKGROUND:Thrombocytopenia (TP) has been shown to be an independent predictor of mortality in the intensive care unit (ICU) patients. Studies are lacking in the neurological ICU (NICU) population. The aim was to evaluate the incidence of TP in NICU and the relationship between TP and outcomes. METHODS:We conducted a retrospective multicenter study of prospectively collected data of all patients admitted to the NICU between 2014 and 2015 from a large database (eICU Collaborative Research Database). The main exposure was TP at admission and TP developed during NICU stay. Multivariable logistic regression and Cox proportional hazard models were used to evaluate the relationship of TP at admission and platelet course with hospital mortality. The primary outcome was hospital mortality. RESULTS

SUBMITTER: Zhou D 

PROVIDER: S-EPMC7260747 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature