Age-related changes in the gut microbiota and the core gut microbiome of healthy Thai humans.

ABSTRACT: The gut microbial diversity of Thai people was investigated between two large cohorts, adult and elderly subjects, from the middle region of Thailand; the cohorts were divided into different age groups of healthy adult (73) and elderly subjects (47). The diversities of the groups were characterized using a pyrosequencing technique with primers targeting the V6-V8 region of the 16S rRNA gene, and a significant decrease in the Firmicutes and Bacteroidetes ratio from 7.3 to 4.5 was observed with increased age. The microbiota of the adult and elderly groups had a significantly higher abundance of the phylum Actinobacteria, including the three species Bifidobacterium adolescentis, Bifidobacterium longum and Bifidobacterium

SUBMITTER: La-Ongkham O 

PROVIDER: S-EPMC7261292 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature