Pattern and risk factors of local recurrence after nephroureterectomy for upper tract urothelial carcinoma.

ABSTRACT:

Purpose

This study aims to identify predictive local recurrence risk factors and site-specific local recurrence pattern of upper tract urothelial carcinoma (UTUC) with different primary tumor locations.

Methods

Three hundred and eighty-nine UTUC patients with radical nephroureterectomy were included in this study. Univariate and multivariate Cox proportional hazards regressions were performed to measure the risk of local recurrence. We also mapped the position of local recurrence sites stratified by primary tumor locations.

Results

A total of 73 patients (18.7%) developed local recurrence within a median follow-up of 41 months (range, 3-80 months). For patients with local recurrence, the median interval of local recurrence was 9 months. Ureter tumor, multifocality, T

SUBMITTER: Li X 

PROVIDER: S-EPMC7261378 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature