Prognostic value of neuron-specific enolase for small cell lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Neuron-specific enolase (NSE) has become a widely used and easily attainable laboratory assay of small cell lung cancer (SCLC). However, the prognostic value of NSE for SCLC patients remains controversial. The aim of the study was to evaluate the correlation between elevated serum NSE before therapy and survival of SCLC patients.

Methods

We performed a systematic review and meta-analysis. A systematic literature search was conducted in PubMed, Embase, and the Cochrane Central Register from the inception dates to December 2019. Eligible articles were included according to inclusion and exclusion criteria; then, data extraction and quality assessment were performed. The primary outcome was overall survival (OS), and the secondary endpoint was progression-free surviv

SUBMITTER: Tian Z 

PROVIDER: S-EPMC7261386 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature