Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease.

ABSTRACT:

Background

In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or severe ischemia. A secondary objective of the trial was to assess angina-related health status among these patients.

Methods

We assessed angina-related symptoms, function, and quality of life with the Seattle Angina Questionnaire (SAQ) at randomization, at months 1.5, 3, and 6, and every 6 months thereafter in participants who had been randomly assigned to an invasive treatment strategy (2295 participants) or a conservative strategy (2322). Mixed-effects cumulative probability models within a Bayesian framework were used to estimate differences between the treatment groups. T

SUBMITTER: Spertus JA 

PROVIDER: S-EPMC7261489 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature