Microvascular disease and heart failure with reduced and preserved ejection fraction in type 2 diabetes.

ABSTRACT:

Aims

Identification of patients with type 2 diabetes (T2D) at increased risk of incident heart failure (HF) beyond traditional risk factors such as prior myocardial infarction (MI) might allow selection of patients who would benefit from preventative treatment. Microvascular disease (MiVD) is thought to play a pathophysiological role in the development of HF in T2D; however, its association with new-onset HF with reduced or preserved ejection fraction has not been specifically defined.

Methods and results

Patients in the Genetics of Diabetes Audit and Research Tayside Scotland study were linked to echocardiography, prescriptions, and clinical outcomes. In total, 9141 patients with T2D were identified for analysis. Clinical variables and the presence of retinopathy, nephropat

SUBMITTER: Mordi IR 

PROVIDER: S-EPMC7261547 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature