Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.

ABSTRACT: Long-term outcomes remain suboptimal following pediatric liver transplantation; only one third of children have normal biochemical liver function without immunosuppressant comorbidities 10 years posttransplant. We examined the association between an index of neighborhood socioeconomic deprivation with graft and patient survival using the Scientific Registry of Transplant Recipients. We included children <19 years who underwent liver transplantation between January 1, 2008 to December 31, 2013 (n = 2868). Primary exposure was a neighborhood socioeconomic deprivation index-linked via patient home ZIP code-with a range of 0-1 (values nearing 1 indicate neighborhoods with greater socioeconomic deprivation). Primary outcome measures were graft failure and death, censored at 10 years posttranspl

SUBMITTER: Wadhwani SI 

PROVIDER: S-EPMC7261648 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature