The circadian clock shapes the <i>Arabidopsi</i>s transcriptome by regulating alternative splicing and alternative polyadenylation.

ABSTRACT: The circadian clock in plants temporally coordinates biological processes throughout the day, synchronizing gene expression with diurnal environmental changes. Circadian oscillator proteins are known to regulate the expression of clock-controlled plant genes by controlling their transcription. Here, using a high-throughput RNA-Seq approach, we examined genome-wide circadian and diurnal control of the Arabidopsis transcriptome, finding that the oscillation patterns of different transcripts of multitranscript genes can exhibit substantial differences and demonstrating that the circadian clock affects posttranscriptional regulation. In parallel, we found that two major posttranscriptional mechanisms, alternative splicing (AS; especially intron retention) and alternative polyadenylation

SUBMITTER: Yang Y 

PROVIDER: S-EPMC7261790 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature