Paradoxical low-flow phenotype in hospitalized heart failure with preserved ejection fraction.

ABSTRACT:

Background

Low flow (LF) in heart failure with preserved ejection fraction (HFpEF) is a paradox but is associated with worse prognosis. Determinants of LF in HFpEF have not been clarified but their assessment could corroborate recognition and definition of such a paradoxical condition.

Methods

A cohort of 193 patients hospitalized with HFpEF was retrospectively studied and divided in a group with LF (N = 45), defined by a left ventricular (LV) stroke volume index (SVI) < 30 ml/m², and a group with normal flow (N = 148). A small LV cavity was pre-defined as LV end diastolic diameter index (EDDI) below median values (<25 mm/m² for males and <26 mm/m² for females). Right ventricular dysfunction (RVD) was defined as the ratio between tricuspid an

SUBMITTER: Mele D 

PROVIDER: S-EPMC7262439 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature