Aetiology of nutritional rickets in rural Bangladeshi children.

ABSTRACT:

Objectives

A high prevalence of rickets of unknown aetiology has been reported in Chakaria, Bangladesh. Classically, rickets is caused by vitamin D deficiency but increasing evidence from Africa and Asia points towards other nutritional deficiencies or excessive exposure to some metals. The aim of this study was to investigate the aetiology of rickets in rural Bangladeshi children.

Methods

64 cases with rickets-like deformities were recruited at first presentation together with age-sex-village matched controls. Data and sample acquisition included anthropometry, radiographs, fasted plasma and urinary samples, 24 h weighed dietary intake together with a 24 h urine collection, and ¹³C-breath tests to detect Helicobacter (H.) pylori infection.

Results

One chil

SUBMITTER: Ahmed S 

PROVIDER: S-EPMC7262584 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature