Statistical analyses and quality of individual participant data network meta-analyses were suboptimal: a cross-sectional study.

ABSTRACT:

Background

Network meta-analyses using individual participant data (IPD-NMAs) have been increasingly used to compare the effects of multiple interventions. Although there have been many studies on statistical methods for IPD-NMAs, it is unclear whether there are statistical defects in published IPD-NMAs and whether the reporting of statistical analyses has improved. This study aimed to investigate statistical methods used and assess the reporting and methodological quality of IPD-NMAs.

Methods

We searched four bibliographic databases to identify published IPD-NMAs. The methodological quality was assessed using AMSTAR-2 and reporting quality assessed based on PRISMA-IPD and PRISMA-NMA. We performed stratified analyses and correlation analyses to explore the factors that might

SUBMITTER: Gao Y 

PROVIDER: S-EPMC7262764 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature