Cross-sectional and longitudinal study of the impact of posterior meniscus horn lesions on adjacent cartilage composition, patient-reported outcomes and gait biomechanics in subjects without radiographic osteoarthritis.

ABSTRACT:

Objective

The aim of this study was to assess cross-sectional and longitudinal effects of meniscal lesions on adjacent cartilage T_1ρ and T₂ relaxation times, patient-reported outcomes and gait biomechanics.

Design

Thirty patients with no cartilage morphological defects reported by Whole Organ MRI Score (WORMS) magnetic resonance imaging (MRI) grading and no radiographic osteoarthritis (OA) (Kellgren--Lawrence (KL) ≤ 1) were selected, 15 with posterior meniscus horn lesions and 15 matched controls without meniscal lesions. All were imaged on a 3T MR scanner for three consecutive years, except those who dropped from the study. Sagittal and frontal plane kinematic gait data were acquired at baseline. The Knee Injury and Osteoarthritis Outcome Score (KOOS)

SUBMITTER: Russell C 

PROVIDER: S-EPMC7263373 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature