Ontology highlight
ABSTRACT:
SUBMITTER: Woolsey C
PROVIDER: S-EPMC7263506 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
bioRxiv : the preprint server for biology 20200517
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an unprecedented global pandemic of COVID-19. Animal models are urgently needed to study the pathogenesis of COVID-19 and to screen candidate vaccines and treatments. Nonhuman primates (NHP) are considered the gold standard model for many infectious pathogens as they usually best reflect the human condition. Here, we show that African green monkeys support a high level of SARS-CoV-2 replication and develop pronounced ...[more]