Continuous EEG Findings in Autoimmune Encephalitis.

ABSTRACT:

Purpose

Autoimmune encephalitis (AE) is a cause of new-onset seizures, including new-onset refractory status epilepticus, yet there have been few studies assessing the EEG signature of AE.

Methods

Multicenter retrospective review of patients diagnosed with AE who underwent continuous EEG monitoring.

Results

We identified 64 patients (male, 39%; white, 49%; median age, 44 years); of whom, 43 (67%) were antibody-proven AE patients. Of the patients with confirmed antibody AE, the following were identified: N-methyl-D-aspartate receptor (n = 17, 27%), voltage-gated potassium channel (n = 16, 25%), glutamic acid decarboxylase (n = 6, 9%), and other (n = 4, 6%). The remaining patients were classified as probable antibody-negative AE (n = 11, 17%), definite limbic encephalit

SUBMITTER: Moise AM 

PROVIDER: S-EPMC7263965 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature