Augmenting usual care SSRIs with cognitive behavioral therapy for insomnia to improve depression outcomes in youth: Design of a randomized controlled efficacy-effectiveness trial.

ABSTRACT:

Importance

Extant treatments for youth depression are only modestly effective. Alternative approaches are needed to improve health outcomes. A novel approach to improve depression outcomes is suggested by epidemiological studies finding that insomnia often predates and may contribute to depression risk. We test whether treating insomnia among youth starting a new course of SSRI antidepressants improves depression outcomes. This paper describes our study design.

Design

2-arm randomized controlled efficacy-effectiveness trial.

Setting

A large non-profit health maintenance organization.

Participants

165 adolescents aged 12-19 with research-confirmed depression and insomnia diagnoses, starting a new episode of selective serotonin reuptake inhibitor (SSRI) antidepre

SUBMITTER: Clarke G 

PROVIDER: S-EPMC7263975 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature