Perspectives of Pitocin administration on behavioral outcomes in the pediatric population: recent insights and future implications.

ABSTRACT: Oxytocin plays an important role in the regulation of parturition as this peptide hormone promotes uterine smooth muscle contractility in gravid women undergoing labor. Here, we review the impact of Pitocin administration on behavioral outcomes in the pediatric population. Pitocin is a synthetic preparation of oxytocin widely used in the obstetric practice for the management of labor and postpartum hemorrhage. We begin by tracing the neuroanatomy of oxytocin-containing cells from an evolutionary perspective and then summarize key findings on behavioral and neural activity reported from offspring dosed with Pitocin during vaginal delivery. Finally, we discuss future directions that are experimentally tractable for understanding the developmental consequences of Pitocin administration on a s

SUBMITTER: Torres G 

PROVIDER: S-EPMC7264063 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature