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COVID-19 in a high-risk dual heart and kidney transplant recipient.


ABSTRACT: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly infecting people worldwide, resulting in the infectious disease coronavirus disease 19 (COVID-19) that has been declared a pandemic. Much remains unknown about COVID-19, including its effects on solid organ transplant (SOT) recipients. Given their immunosuppressed state, SOT recipients are presumed to be at high risk of complications with viral infections such as SARS-CoV-2. Limited case reports in single SOT recipients, however, have not suggested a particularly severe course in this population. In this report, we present a dual-organ (heart/kidney) transplant recipient who was found to have COVID-19 and, despite the presence of a number of risk factors for poor outcomes, had a relatively mild clinical course.

SUBMITTER: Hsu JJ 

PROVIDER: S-EPMC7264582 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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COVID-19 in a high-risk dual heart and kidney transplant recipient.

Hsu Jeffrey J JJ   Gaynor Pryce P   Kamath Megan M   Fan Ashley A   Al-Saffar Farah F   Cruz Daniel D   Nsair Ali A  

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20200622 7


The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly infecting people worldwide, resulting in the infectious disease coronavirus disease 19 (COVID-19) that has been declared a pandemic. Much remains unknown about COVID-19, including its effects on solid organ transplant (SOT) recipients. Given their immunosuppressed state, SOT recipients are presumed to be at high risk of complications with viral infections such as SARS-CoV-2. Limited case reports in single SOT recipients,  ...[more]

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