Deep learning-based hologram generation using a white light source.

ABSTRACT: Digital holographic microscopy enables the recording of sample holograms which contain 3D volumetric information. However, additional optical elements, such as partially or fully coherent light source and a pinhole, are required to induce diffraction and interference. Here, we present a deep neural network based on generative adversarial network (GAN) to perform image transformation from a defocused bright-field (BF) image acquired from a general white light source to a holographic image. Training image pairs of 11,050 for image conversion were gathered by using a hybrid BF and hologram imaging technique. The performance of the trained network was evaluated by comparing generated and ground truth holograms of microspheres and erythrocytes distributed in 3D. Holograms generated from BF imag

SUBMITTER: Go T 

PROVIDER: S-EPMC7265409 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature