Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial.

ABSTRACT:

Background

Palliative care improves quality of life in patients with heart failure. Whether men and women with heart failure derive similar benefit from palliative care interventions remains unknown.

Methods

In a secondary analysis of the PAL-HF trial (Palliative Care in Heart Failure), we analyzed differences in quality of life among men and women with heart failure and assessed for differential effects of the palliative care intervention by sex. Differences in clinical characteristics and quality-of-life metrics were compared between men and women at serial time points. The primary outcome was change in Kansas City Cardiomyopathy Questionnaire score between baseline and 24 weeks.

Results

Among the 71 women and 79 men, there was a significant difference in baseline K

SUBMITTER: Truby LK 

PROVIDER: S-EPMC7265474 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature