Core Outcome Set for Clinical Trials of COVID-19 Based on Traditional Chinese and Western Medicine.

ABSTRACT:

Background

Development of a core outcome set (COS) for clinical trials for COVID-19 is urgent because of the pandemic wreaking havoc worldwide and the heterogeneity of outcomes in clinical trials.

Methods

A preliminary list of outcomes was developed after a systematic review of protocols of clinical trials for COVID-19. Then, two rounds of the Delphi survey were conducted. Stakeholders were traditional Chinese medicine (TCM) experts, Western medicine (WM) experts, nurses, and the public. Patients with confirmed COVID-19 were also invited to participate in a questionnaire written in understandable language. Then different stakeholders participated in a consensus meeting by video conference to vote.

Results

Ninety-seven eligible study protocols were identified from 160

SUBMITTER: Qiu R 

PROVIDER: S-EPMC7265660 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature