Gray Matter Volume Covariance Networks, Social Support, and Cognition in Older Adults.

ABSTRACT:

Objective

We examined the neural substrates of social support in older adults. Social support is associated with better outcomes in many facets of aging-including cognitive and functional health-but the underlying neural substrates remain largely unexplored.

Methods

Voxel-based morphometry and multivariate statistics were used to identify gray matter volume covariance networks associated with social support in 112 older adults without dementia (M age = 74.6 years, 50% female), using the Medical Outcomes Study Social Support Survey.

Results

A gray matter network associated with overall social support was identified and included prefrontal, hippocampal, amygdala, cingulate, and thalamic regions. A gray matter network specifically associated with tangible social support

SUBMITTER: Cotton K 

PROVIDER: S-EPMC7265803 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature