Reducing socio-economic inequalities in all-cause mortality: a counterfactual mediation approach.

ABSTRACT:

Background

Socio-economic inequalities in mortality are well established, yet the contribution of intermediate risk factors that may underlie these relationships remains unclear. We evaluated the role of multiple modifiable intermediate risk factors underlying socio-economic-associated mortality and quantified the potential impact of reducing early all-cause mortality by hypothetically altering socio-economic risk factors.

Methods

Data were from seven cohort studies participating in the LIFEPATH Consortium (total n = 179 090). Using both socio-economic position (SEP) (based on occupation) and education, we estimated the natural direct effect on all-cause mortality and the natural indirect effect via the joint mediating role of smoking, alcohol intake, dietary patterns, physi

SUBMITTER: Laine JE 

PROVIDER: S-EPMC7266549 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature