Afternoon distraction: a high-saturated-fat meal and endotoxemia impact postmeal attention in a randomized crossover trial.

ABSTRACT:

Background

Saturated-fat intake and endotoxemia can impair cognition. However, their acute impact on cognitive performance is unknown.

Objective

This study assessed the impact of 2 high-fat meals and endotoxemia on attention.

Methods

In this double-blind, randomized crossover trial, 51 women (n = 32 breast cancer survivors, n = 19 noncancer controls; mean ± SD age: 53 ± 8 y) completed the Continuous Performance Test (CPT) and had their blood drawn to assess endotoxemia markers LPS binding protein (LBP), soluble CD14 (sCD14), and the LBP to sCD14 ratio 1 h prior to eating either a high-saturated-fat meal or a high-oleic-sunflower-oil meal. Women again completed the CPT 5 h postmeal. At 1 to 4 wk later, women completed the same protocol but consumed the other meal.

R

SUBMITTER: Madison AA 

PROVIDER: S-EPMC7266694 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature