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Cephalopod-inspired optical engineering of human cells.

ABSTRACT: Although many animals have evolved intrinsic transparency for the purpose of concealment, the development of dynamic, that is, controllable and reversible, transparency for living human cells and tissues has remained elusive to date. Here, by drawing inspiration from the structures and functionalities of adaptive cephalopod skin cells, we design and engineer human cells that contain reconfigurable protein-based photonic architectures and, as a result, possess tunable transparency-changing and light-scattering capabilities. Our findings may lead to the development of unique biophotonic tools for applications in materials science and bioengineering and may also facilitate an improved understanding of a wide range of biological systems.

SUBMITTER: Chatterjee A

PROVIDER: S-EPMC7266819 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Cephalopod-inspired optical engineering of human cells.

Chatterjee Atrouli A Cerna Sanchez Juana Alejandra JA Yamauchi Toyohiko T Taupin Vanessa V Couvrette Justin J Gorodetsky Alon A AA

Nature communications 20200602 1

Although many animals have evolved intrinsic transparency for the purpose of concealment, the development of dynamic, that is, controllable and reversible, transparency for living human cells and tissues has remained elusive to date. Here, by drawing inspiration from the structures and functionalities of adaptive cephalopod skin cells, we design and engineer human cells that contain reconfigurable protein-based photonic architectures and, as a result, possess tunable transparency-changing and li ...[more]

PMID: 32488070

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