Dataset Information
Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial.
Ontology highlight
ABSTRACT:
SUBMITTER: Maes B
PROVIDER: S-EPMC7267751 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial.
Trials 20200603 1
<h4>Objectives</h4>The purpose of this study is to test the safety and effectiveness of individually or simultaneously blocking IL-6, IL-6 receptor and IL-1 versus standard of care on blood oxygenation and systemic cytokine release syndrome in patients with COVID-19 coronavirus infection and acute hypoxic respiratory failure and systemic cytokine release syndrome.<h4>Trial design</h4>A phase 3 prospective, multi-center, interventional, open label, 6-arm 2x2 factorial design study.<h4>Participant ...[more]
