Neural oscillations and connectivity characterizing the state of tonic experimental pain in humans.

ABSTRACT: Pain is a complex phenomenon that is served by neural oscillations and connectivity involving different brain areas and frequencies. Here, we aimed to systematically and comprehensively assess the pattern of neural oscillations and connectivity characterizing the state of tonic experimental pain in humans. To this end, we applied 10-min heat pain stimuli consecutively to the right and left hand of 39 healthy participants and recorded electroencephalography. We systematically analyzed global and local measures of oscillatory brain activity, connectivity, and graph theory-based network measures during tonic pain and compared them to a nonpainful control condition. Local measures showed suppressions of oscillatory activity at alpha frequencies together with stronger connectivity at alpha and

SUBMITTER: Nickel MM 

PROVIDER: S-EPMC7267966 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature