Accurate prediction of individual subject identity and task, but not autism diagnosis, from functional connectomes.

ABSTRACT: Despite enthusiasm about the potential for using fMRI-based functional connectomes in the development of biomarkers for autism spectrum disorder (ASD), the literature is full of negative findings-failures to distinguish ASD functional connectomes from those of typically developing controls (TD)-and positive findings that are inconsistent across studies. Here, we report on a new study designed to either better differentiate ASD from TD functional connectomes-or, alternatively, to refine our understanding of the factors underlying the current state of affairs. We scanned individuals with ASD and controls both at rest and while watching videos with social content. Using multiband fMRI across repeat sessions, we improved both data quantity and scanning duration by collecting up to 2 hr of data

SUBMITTER: Byrge L 

PROVIDER: S-EPMC7268028 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature