Brain oscillatory activity as a biomarker of motor recovery in chronic stroke.

ABSTRACT: In the present work, we investigated the relationship of oscillatory sensorimotor brain activity to motor recovery. The neurophysiological data of 30 chronic stroke patients with severe upper-limb paralysis are the basis of the observational study presented here. These patients underwent an intervention including movement training based on combined brain-machine interfaces and physiotherapy of several weeks recorded in a double-blinded randomized clinical trial. We analyzed the alpha oscillations over the motor cortex of 22 of these patients employing multilevel linear predictive modeling. We identified a significant correlation between the evolution of the alpha desynchronization during rehabilitative intervention and clinical improvement. Moreover, we observed that the initial alpha desy

SUBMITTER: Ray AM 

PROVIDER: S-EPMC7268060 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature