Comparative measurement properties of constant work rate cycling and the endurance shuttle walking test in COPD: the TORRACTO^® clinical trial.

ABSTRACT:

Background

Exercise tolerance is an important endpoint in chronic obstructive pulmonary disease (COPD) clinical trials. Little is known about the comparative measurement properties of constant work rate cycle ergometry (CWRCE) and the endurance shuttle walking test (ESWT). The objective of this sub-analysis of the TORRACTO^® study was to directly compare the endurance measurement properties of CWRCE and ESWT in patients with COPD in a multicentre, multinational setting. We predicted that both tests would be similarly reliable, but that the ESWT would be more responsive to bronchodilation than CWRCE.

Methods

This analysis included 151 patients who performed CWRCE and ESWT at baseline and week 6 after receiving once-daily placebo, tiotropium/olodaterol (T/O) 2.5/5 μg

SUBMITTER: Maltais F 

PROVIDER: S-EPMC7268161 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature