Targeted-gene sequencing of an undifferentiated gallbladder carcinoma: a case report.

ABSTRACT:

Background

Undifferentiated carcinomas of the gallbladder are extremely rare. Most undifferentiated carcinomas are accompanied by adjacent foci of other conventional carcinomas, and a transition zone is shared between them. However, genetic alterations of undifferentiated gallbladder carcinoma and the similarities or differences between the undifferentiated carcinoma and the foci conventional carcinoma are unknown.

Case presentation

Herein, we report a case of undifferentiated gallbladder carcinoma with osteoclast-like giant cells with invasion into the liver, duodenum, and stomach in a 56-year-old man. The tumor was microscopically formed from the tubular adenocarcinoma (< 5% of the entire tumor), the undifferentiated carcinoma, and a transition zone between them. Four soma

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC7268304 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature