Association between Epstein-Barr virus infection and gastric cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Numerous studies conducted over the past 30 years have pointed to the presence of Epstein-Barr virus (EBV) in gastric cancer samples. This study was aimed to provide a meta-analytic review of the prevalence of EBV in gastric cancer patients, and to clarify the relationship between EBV infection and gastric cancer.

Methods

A literature search was performed electronically using online databases for English language publications until July 1, 2019. The pooled EBV prevalence and 95% confidence intervals (CIs) were estimated using a random-effects model. To determine the association between EBV and gastric cancer, pooled odds ratio (OR) and its 95% CI were computed for case-control studies. Two separate analyses were performed on data from case-control studies with mat

SUBMITTER: Tavakoli A 

PROVIDER: S-EPMC7268387 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature